mofo

1. (abbr.) mother-fucker 2. (n.) One who is hard-core
Dat man is one bad-ass mofo, yo!
by k1 October 03, 2001
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mofo

A word used instead of mother fucker. It still has the same meaning, but the impact is not as big. OR It could be like saying that guy is the shit!
Billy Bob: Goddammit! I wanna fuck something up! That fucking mofo stole my fucking wallet!! Shit man! OR Sally Sue: Damn, you be tite for dating that mofo!
by I Luff Yooh Bitches January 05, 2009
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mofo

1) motherfucker 2)niall horan used this to call his fans crazy mofos
by stakia March 10, 2018
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mofo

1. Short version of the word mother-fucker 2. Industry nickname for San Francisco based law firm Morrison and Foerster. The firm still uses the domain name mofo.com for its IP network services. The firm actually rebranded itself MoFo for a while until it realized that the strategy was less than successful.
John just got a job over at mofo after graduating from Law School.
by mlu December 25, 2005
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mofo

A sign of respect. Not to be confused with motherfucker, which is clearly an insult.
Girl: Yo mofo, what's poppin'? Guy: Just chattin' it up with my pet chincilla, you?
by marjrealtalk September 26, 2011
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mofo

by crazyMOFEFFA August 27, 2008
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mofo

Short for Motherfucker = someome who is ridiculously awesome. Also, (30 Seconds to Mars') Tomo Milicevic's favorite word.
That Tomo is one crazy mofo! Have you seen him play live? Amazing.
by thevenomousone February 26, 2010
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